Toss butternut squash with olive oil, salt, pepper, cumin, and smoked paprika. Spread on a baking sheet.
Roast for 20 minutes or until tender.
Heat a skillet over medium heat. Place a tortilla in the skillet, add roasted squash, vegan cheese (if using), and cilantro. Top with another tortilla.
Cook until golden brown, about 2-3 minutes per side.