Preheat your oven to 350°F (175°C). Grease a loaf pan.
In a large mixing bowl, combine the flour, sugar, baking powder, baking soda, and salt.
Add the chopped cranberries and orange zest to the dry ingredients and mix well.
In another bowl, mix the orange juice, vegetable oil, and vanilla extract.
Pour the wet ingredients into the dry ingredients and stir until just combined.
Pour the batter into the prepared loaf pan and spread it evenly.
Bake for 50 minutes or until a toothpick inserted into the center comes out clean.
Let the bread cool in the pan for 10 minutes, then transfer it to a wire rack to cool completely.